Manisha Patel Selected Research

Grape Seed Extract

12/2015	Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.
1/2014	Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.

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Manisha Patel Research Topics

Disease

23	Epilepsy (Aura) 04/2024 - 04/2008
14	Status Epilepticus (Complex Partial Status Epilepticus) 04/2024 - 01/2005
13	Seizures (Absence Seizure) 01/2021 - 03/2004
13	Parkinson Disease (Parkinson's Disease) 01/2021 - 09/2004
10	Measles 01/2021 - 01/2017
9	Neuroinflammatory Diseases 04/2024 - 01/2017
9	Temporal Lobe Epilepsy 01/2018 - 04/2008
8	Mumps 01/2021 - 01/2017
7	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2014 - 02/2005
6	Infections 01/2021 - 04/2015
6	Rubella (German Measles) 03/2020 - 01/2017
5	Cognitive Dysfunction 08/2023 - 03/2002
5	Inflammation (Inflammations) 01/2021 - 08/2015
5	Neoplasms (Cancer) 01/2019 - 06/2006
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 11/2008
3	Parkinsonian Disorders (Parkinsonism) 01/2021 - 04/2007
3	Whooping Cough (Pertussis) 11/2016 - 01/2008
3	Meningococcal Infections 10/2015 - 05/2015
3	Drug Resistant Epilepsy 11/2014 - 08/2008
2	Neurodevelopmental Disorders 01/2021 - 01/2016
2	Stroke (Strokes) 01/2021 - 03/2009
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2021 - 03/2016
2	Disease Progression 01/2019 - 07/2017
2	Hypoxia (Hypoxemia) 09/2017 - 07/2003
2	Ketosis 11/2014 - 08/2008
2	Hemorrhage 07/2010 - 04/2003
1	Brain Diseases (Brain Disorder) 04/2024
1	Tuberous Sclerosis (Bourneville's Disease) 11/2023
1	Anemia 07/2023
1	Dental Plaque 05/2023
1	COVID-19 01/2022

Drug/Important Bio-Agent (IBA)

16	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2023 - 10/2002
15	AntioxidantsIBA 04/2024 - 10/2002
12	VaccinesIBA 01/2021 - 01/2008
11	Kainic Acid (Kainate)IBA 04/2024 - 03/2004
9	Proteins (Proteins, Gene)FDA Link 11/2023 - 12/2004
7	Measles-Mumps-Rubella Vaccine (MMR Vaccine)IBA 01/2021 - 01/2017
7	Biomarkers (Surrogate Marker)IBA 01/2019 - 06/2006
6	Glutathione (Reduced Glutathione)IBA 04/2024 - 05/2007
6	Pilocarpine (Ocusert)FDA LinkGeneric 08/2023 - 12/2010
5	AEOL 10150IBA 08/2023 - 10/2002
4	Nerve AgentsIBA 08/2023 - 07/2017
4	MetalloporphyrinsIBA 01/2021 - 10/2002
4	Superoxides (Superoxide)IBA 12/2015 - 04/2003
4	Superoxide DismutaseIBA 03/2012 - 03/2002
3	ManganeseIBA 01/2024 - 04/2003
3	PorphyrinsIBA 08/2023 - 04/2003
3	CytokinesIBA 01/2021 - 08/2015
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 12/2004
3	ParaquatIBA 08/2013 - 07/2003
3	Mitochondrial DNA (mtDNA)IBA 12/2010 - 04/2005
3	IronIBA 11/2008 - 09/2004
3	Aconitate Hydratase (Aconitase)IBA 04/2005 - 03/2004
2	Dimercaprol (B.A.L.)FDA Link 04/2024 - 01/2017
2	Glutamate-Cysteine LigaseIBA 04/2024 - 01/2017
2	EnzymesIBA 04/2024 - 09/2004
2	SomanIBA 08/2023 - 01/2019
2	Isoflurophate (DFP)FDA Link 08/2023 - 01/2018
2	Sirtuin 3IBA 01/2023 - 01/2018
2	NF-kappa B (NF-kB)IBA 01/2022 - 04/2003
2	Cysteine (L-Cysteine)FDA Link 01/2022 - 10/2016
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022 - 01/2005
2	Ion Channels (Ion Channel)IBA 01/2021 - 11/2014
2	Sodium Channels (Sodium Channel)IBA 01/2021 - 03/2016
2	Oxidants (Oxidizing Agents)IBA 01/2021 - 03/2004
2	Rubella VaccineIBA 03/2020 - 10/2019
2	Drug CombinationsIBA 01/2019 - 07/2017
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2018 - 09/2004
2	Immunoglobulins (Immunoglobulin)IBA 01/2018 - 04/2015
2	Caffeine (No Doz)FDA LinkGeneric 09/2017 - 01/2016
2	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 11/2016 - 06/2015
2	Diphtheria Toxoid (Vaccine, Diphtheria)FDA Link 11/2016 - 06/2015
2	Amino Acids FDA Link 10/2016 - 01/2010
2	LipidsIBA 01/2016 - 12/2004
2	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 12/2015 - 12/2009
2	Grape Seed ExtractIBA 12/2015 - 01/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2014 - 01/2010
2	Neurotransmitter Agents (Neurotransmitter)IBA 11/2014 - 01/2010
2	HerbicidesIBA 08/2013 - 12/2009
2	AEOL 11207IBA 03/2012 - 04/2007
2	Adenosine Triphosphate (ATP)IBA 03/2012 - 01/2010
2	Glutathione Disulfide (GSSG)FDA LinkGeneric 12/2010 - 01/2006
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 04/2007 - 09/2004
1	Cysteamine (Mercaptamine)FDA Link 04/2024
1	trans-sodium crocetinate (crocetin)IBA 11/2023
1	Tuberous Sclerosis Complex 2 ProteinIBA 11/2023
1	Tuberous Sclerosis Complex 1 ProteinIBA 11/2023
1	Mechanistic Target of Rapamycin Complex 1IBA 11/2023
1	Hemoglobins (Hemoglobin)IBA 07/2023
1	GlucosyltransferasesIBA 05/2023
1	glucosyltransferase D (GtfD)IBA 05/2023
1	Insulin (Novolin)FDA Link 01/2022
1	lotrafilcon BIBA 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	Biocompatible Materials (Biomaterials)IBA 01/2022

Therapy/Procedure

18	Therapeutics 01/2021 - 08/2008
5	Ketogenic Diet 09/2018 - 08/2008
2	Drug Therapy (Chemotherapy) 03/2017 - 04/2015
2	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 07/2012 - 08/2008
1	Injections 08/2023